Total hCG Versus Free β-hCG Combined with Alpha-fetoprotein for Down Syndrome Screening in Taiwan
نویسندگان
چکیده
منابع مشابه
Human choriogonadotropin (hCG): comparisons between determinations of intact hCG, free hCG beta-subunit, and "total" hCG + beta in serum during the first half of high-risk pregnancy.
We have studied the concentrations of intact human choriogonadotropin (hCG) and the free hCG beta-subunit in blood samples from singleton pregnancies at risk for habitual or threatened abortion. The samples were obtained weekly between the 6th and 12th weeks and in the 14th and 16th weeks of gestational age. The concentrations of intact hCG, of the free hCG beta-subunit, and of "total" hCG (i.e...
متن کاملStability of free beta-hCG in the routine screening of Down syndrome in the first trimester of pregnancy.
Stability of free beta-human chorionic gonadotropin in maternal blood upon storage at ambient and refrigerator temperatures as well as stability under conditions simulating postal transport were studied. A group of 26 women in the first trimester of pregnancy were included in the study, blood samples were taken during the routine check-up. Blood samples were aliquoted stored in different condit...
متن کاملHyperglycosylated human chorionic gonadotropin (invasive trophoblast antigen) immunoassay: A new basis for gestational Down syndrome screening.
BACKGROUND Serum human chorionic gonadotropin (hCG) and hCG free beta-subunit tests are used in combination with unconjugated estriol and alpha-fetoprotein in the triple screen test, and with the addition of inhibin-A in the quadruple marker test for detecting Down syndrome in the second trimester of pregnancy. These tests have a limited detection rate for Down syndrome: approximately 40% for h...
متن کاملMaternal serum PAPP-A and free β-hCG at 12, 22 and 32 weeks' gestation in screening for pre-eclampsia.
OBJECTIVE To examine the distribution of maternal serum pregnancy-associated plasma protein-A (PAPP-A) and free β-human chorionic gonadotropin (β-hCG) at 12, 22 and 32 weeks' gestation in singleton pregnancies which develop pre-eclampsia (PE) and examine the performance of these biomarkers in screening for PE. METHODS Serum PAPP-A and free β-hCG were measured in 94 989 cases at 11-13 weeks, 7...
متن کاملIntra - group diffuse light in compact groups of galaxies . HCG 79 , HCG 88 and HCG 95
Deep B and R images of three Hickson Compact Groups, HCG 79, HCG 88 and HCG 95, were analyzed using a new wavelet technic to measure possible intra-group diffuse light present in these systems. The method used, OV WAV, is a wavelet technic particularly suitable to detect low-surface brightness extended structures, down to a S/N = 0.1 per pixel, which corresponds to a 5-σ-detection level in wave...
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ژورنال
عنوان ژورنال: Taiwanese Journal of Obstetrics and Gynecology
سال: 2007
ISSN: 1028-4559
DOI: 10.1016/s1028-4559(08)60025-x